排列三
排列三医学部助理教授、副研究员
2005 - 2010 排列三医学部 医学学士
2011 - 2015 Karolinska Institutet 博士
2016 - 2017 Scripps Research Institute 博士后
2017 - 2019 University of California San Diego 博士后
2020 - 现在 排列三医学部 副研究员
（1） 抑郁症的发病与治疗机制研究
（2） 躁狂抑郁双相情感障碍的发病与治疗机制研究
（3） 精神病类药物基因组学
（4） 体外诱导干细胞模型对精神疾病病因病理的研究
美国试行专利：62/757,686: Method to predict response to neuropsychiatric drugs using variation in the serotonin 7 receptor (HTR7) gene。
1. Maria Scherma, Johanna S. Qvist, Arun Asok, Shao-shan C. Huang, Paolo Masia, Matteo Deidda, Ya B. Wei, Rajesh K. Soni, Walter Fratta, Paola Fadda, Eric R. Kandel, Denise B. Kandel, and Philippe A. Melas. Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine. Proc Natl Acad Sci U S A. 2020 May 5;117(18):9991-10002. PMID:32312805
2. Liu JJ*, Wei YB*, Strawbridge R, Bao Y, Chang S, Shi L, Que J, Gadad BS, Trivedi MH, Kelsoe JR, Lu L. Peripheral cytokine levels and response to antidepressant treatment in depression: a systematic review and meta-analysis. Mol Psychiatry. 2019 Aug 19. doi: 10.1038/s41380-019-0474-5. PMID:31427752. *Shared first authorship.
3. Wei YB, McCarthy M, Ren H, Carrillo-Roa T, Shekhtman T, DeModena A, Liu JJ, Leckband S, Mors O, Rietschel M, Henigsberg N, Cattaneo A, Binder EB, Aitchison KJ, Keloe JR. A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression. Mol Psychiatry. 2019 Mar 15. doi: 10.1038/s41380-019-0397-1. PMID: 30874608
4. Kumar P, Efstathopoulos P, Millischer V, Olsson E, Wei YB, Brüstle O, Schalling M, Villaescusa JC, ？sby U, Lavebratt C. Mitochondrial DNA copy number is associated with psychosis severity and anti-psychotic treatment. Sci Rep. 2018 Aug 24;8(1):12743. doi: 10.1038/s41598-018-31122-0. PMID: 30143692
5. Melas PA, Qvist JS, Deidda M, Upreti C, Wei YB, Sanna F, Fratta W, Scherma M, Fadda P, Kandel DB, Kandel ER. Cannabinoid Modulation of Eukaryotic Initiation Factors (eIF2α and eIF2B1) and Behavioral Cross-Sensitization to Cocaine in Adolescent Rats. Cell Rep. 2018 Mar 13;22(11):2909-2923. doi: 10.1016/j.celrep.2018.02.065. PMID: 29539420
6. Liu JJ, Wei YB, Forsell Y, Lavebratt C. Stress, depressive status and telomere length: Does social interaction and coping strategy play a mediating role? J Affect Disord. 2017 Nov;222:138-145. doi:V10.1016/j.jad.2017.07.007. Epub 2017 Jul 6. PMID: 28704801
7. Lavebratt C, Herring MP, Liu JJ, Wei YB, Bossoli D, Hallgren M, Forsell Y. Interleukin-6 and depressive symptom severity in response to physical exercise. Psychiatry Res. 2017 Jun;252:270-276. doi: 10.1016/j.psychres.2017.03.012. Epub 2017 Mar 7. PMID: 28285256
8. Wei YB, Liu JJ, ？berg E, Brené S, Wegener G, Mathé AA, Lavebratt C. Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression. Transl Psychiatry. 2016 Aug 16;6:e869. doi: 10.1038/tp.2016.136. PMID: 27529677
9. Wei YB, Melas PA, Villaescusa JC, Liu JJ, Xu N, Christiansen SH, Elbr？nd-Bek H, Woldbye DP, Wegener G, Mathé AA, Lavebratt C. MicroRNA 101b is downregulated in the prefrontal cortex of a genetic model of depression and targets the glutamate transporter SLC1A1 (EAAT3) in vitro. Int J Neuropsychopharmacol. 2016 Aug 9. pii: pyw069. doi: 10.1093/ijnp/pyw069. PMID: 27507301
10. Wei YB, Martinsson L, Liu JJ, Forsell Y, Schalling M, Backlund L, Lavebratt C. hTERT genetic variation in depression.J Affect Disord. 2015 Sep 16;189:62-69. doi: 10.1016/j.jad.2015.09.025. PMID: 26406970.
11. Backlund L, Wei YB, Martinsson L, Melas AP, Liu JJ, Mu N, Ekstr？m T, Schalling M, Lavebratt C. Mood Stabilizers and the Influence on Global Leukocyte DNA Methylation in Bipolar Disorder. Mol Neuropsychiatry 2015;1:76-81. PMID:27602359.
12. Wei YB, Backlund L, Wegener G, Mathé AA, Lavebratt C.Telomerase dysregulation in the hippocampus of a rat model of depression. Normalization by lithium.Int J Neuropsychopharmacol. 2015 Jan 24. pii: pyv002. doi: 10.1093/ijnp/pyv002. PMID:25618407.
13. Wei YB, Melas PA, Wegener G, Mathé AA, Lavebratt C.Antidepressant-Like Effect of Sodium Butyrate is Associated with an Increase in TET1 and in 5-Hydroxymethylation Levels in the Bdnf Gene.Int J Neuropsychopharmacol. 2014 Oct 31;18(2). PMID:25618518.
14. Martinsson L*, Wei YB*, Xu D, Melas PA, Mathé AA, Schalling M, Lavebratt C, Backlund L. Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres. Transl Psychiatry. 2013 May 21; 3:e261. PMID:23695236.*Shared first authorship.
15. Fandi？o-Losada A,Wei YB, Aberg E, Sj？holm LK, Lavebratt C, Forsell Y.Influence of serotonin transporter promoter variation on the effects of separation from parent/partner on depression.J Affect Disord. 2013 Jan 25;144(3):216-24. PMID:22884012.
16. Melas PA,Wei YB, Wong CC, Sj？holm LK, ？berg E, Mill J, Schalling M, Forsell Y, Lavebratt C.Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities.Int J Neuropsychopharmacol. 2013 Aug;16(7):1513-28. PMID:23449091.
17. Melas PA, Lennartsson A, Vakifahmetoglu-Norberg H, Wei YB, ？berg E, Werme M, Rogdaki M, Mannervik M, Wegener G, Brené S, Mathé AA, Lavebratt C. Allele-specific programming of neuropeptide Y (Npy) and epigenetic effects of physical activity in a genetic model of depression. Transl Psychiatry. 2013 May 7;3:e255. doi: 10.1038/tp.2013.31. PMID: 23652932